Description

2,4-Pyrimidinediamine, 6-Ethynyl- (9Ci) is a high-purity, functionalized pyrimidine derivative, identified by CAS number 727651-52-7. This compound serves as a critical pharmaceutical intermediate and key building block in organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology & Proteomics: Serves as a versatile handle for bio-conjugation and probe development via click chemistry (copper-catalyzed azide-alkyne cycloaddition) due to the ethynyl group.
• Material Science: A precursor for constructing functionalized polymers, ligands for catalysis, and organic electronic materials.
• Academic & Contract Research: Essential for fundamental organic chemistry research and custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Product Name	2,4-Pyrimidinediamine, 6-Ethynyl- (9Ci)
CAS No.	727651-52-7
Molecular Formula	C6H7N5
Molecular Weight	149.15 g/mol
Synonyms	6-Ethynylpyrimidine-2,4-diamine; 6-Ethynyl-2,4-pyrimidinediamine; 2,4-Diamino-6-ethynylpyrimidine; 6-Ethynyl-2,4-diaminopyrimidine; 6-Ethynylpyrimidine-2,4-diyldiamine; 727651-52-7; 6-Ethynyl-2,4-pyrimidinediamine (9CI)
EINECS	Contact for details

Quality Control

Our 2,4-Pyrimidinediamine, 6-Ethynyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We support cGMP and ISO compliant production for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.