Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-[4-[[(2,3-Dihydro-1,4-Benzodioxin-6-Yl)Amino]Thioxomethyl]-1-Piperazinyl]-6-Fluoro-1,4-Dihydro-4-Oxo- is a high-purity, complex heterocyclic compound designed for advanced research and development. This molecule is of significant interest in the pharmaceutical industry as a key synthetic intermediate or potential pharmacophore for novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and contract research organizations (CROs) engaged in the discovery of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel antibiotic or antimicrobial agents, leveraging its complex quinoline and piperazine core structure.
• Antibacterial Research: Used as a reference standard or starting material in the development of new fluoroquinolone-class antibacterial compounds.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties of drug candidates.
• Biochemical Research: Acts as a tool compound for investigating specific enzyme inhibition or receptor binding mechanisms in microbiological studies.
• Process Development: Utilized in scaling up synthetic routes for potential Active Pharmaceutical Ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-[4-[[(2,3-Dihydro-1,4-Benzodioxin-6-Yl)Amino]Thioxomethyl]-1-Piperazinyl]-6-Fluoro-1,4-Dihydro-4-Oxo-
CAS No.	727419-85-4
Molecular Formula	C26H24FN5O4S
Molecular Weight	521.56 g/mol
Synonyms	1-Cyclopropyl-6-fluoro-7-(4-{[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]carbonothioyl}piperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1-Cyclopropyl-7-[4-[[(2,3-Dihydro-1,4-Benzodioxin-6-Yl)Amino]Thioxomethyl]-1-Piperazinyl]-6-Fluoro-1,4-Dihydro-4-Oxo-3-Quinolinecarboxylic Acid; Advanced Fluoroquinolone Intermediate; Benzodioxinyl-thioureido Quinoline Derivative
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical research applications. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Quality assurance is supported by modern analytical techniques including HPLC, NMR, and Mass Spectrometry. We operate under a quality management system and can supply material suitable for use under GMP guidelines for pharmaceutical development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified and stored in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.