Description

1,2,4-Triazolo[4,3-A]Pyrimidin-5(1H)-One, 7-Hydroxy- (9Ci) is a high-purity, fused heterocyclic compound serving as a critical advanced pharmaceutical intermediate. Its value lies in its role as a sophisticated building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. This product is essential for research and development chemists and process scale-up teams within the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probe: Serves as a core scaffold for designing molecular probes to study enzyme function and biological pathways.
• Material Science: Investigated for incorporation into advanced polymers and organic electronic materials due to its fused ring structure.
• Academic & Contract Research: Supplied to universities and CROs for fundamental heterocyclic chemistry research and custom synthesis projects.

Basic Information

Product Name	1,2,4-Triazolo[4,3-A]Pyrimidin-5(1H)-One, 7-Hydroxy- (9Ci)
CAS No.	727390-69-4
Molecular Formula	C5H4N4O2
Molecular Weight	152.11 g/mol
Synonyms	7-Hydroxy-[1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-one; 7-Hydroxy-1,2,4-triazolo[4,3-a]pyrimidin-5(1H)-one; 7-Hydroxy-1H-[1,2,4]triazolo[4,3-a]pyrimidin-5-one; 727390-69-4; 1H-[1,2,4]Triazolo[4,3-a]pyrimidin-5-one, 7-hydroxy-; Triazolopyrimidinone derivative
EINECS	Contact for details

Quality Control

Every batch of our 1,2,4-Triazolo[4,3-A]Pyrimidin-5(1H)-One, 7-Hydroxy- (9Ci) is manufactured under a strict quality management system. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by HPLC, NMR, and mass spectrometry. Our quality commitment ensures material consistency and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.