Description

n-(2-Aminophenyl)-4-([[4-(Pyridin-3-Yl)Pyrimidin-2-Yl]Amino]Methyl)Benzamide is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of targeted small-molecule therapeutics. It is primarily sought after by research institutions and pharmaceutical companies engaged in drug discovery and development, particularly in oncology and kinase inhibitor research. The material is supplied to meet the stringent quality requirements of preclinical and clinical-stage manufacturing.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel kinase inhibitors and other targeted cancer therapies.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Biochemical Reagent: Serves as a reference standard or a tool compound in biochemical assays to study specific enzymatic pathways.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and chemical biology.
• Contract Development and Manufacturing (CDMO): Supplied to CDMOs for scale-up synthesis under current Good Manufacturing Practice (cGMP) guidelines for clinical trial material production.

Basic Information

Product Name	n-(2-Aminophenyl)-4-([[4-(Pyridin-3-Yl)Pyrimidin-2-Yl]Amino]Methyl)Benzamide
CAS No.	726169-73-9
Molecular Formula	C23H20N6O
Molecular Weight	396.45 g/mol
Synonyms	4-[[[4-(3-Pyridinyl)-2-pyrimidinyl]amino]methyl]-N-(2-aminophenyl)benzamide; BDBM50164989; N-(2-Aminophenyl)-4-({[4-(pyridin-3-yl)pyrimidin-2-yl]amino}methyl)benzamide; AKOS025310991; Benzamide, N-(2-aminophenyl)-4-[[[4-(3-pyridinyl)-2-pyrimidinyl]amino]methyl]-; FT-0714487; 4-({[4-(Pyridin-3-yl)pyrimidin-2-yl]amino}methyl)-N-(2-aminophenyl)benzamide
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to rigorous quality control protocols to ensure batch-to-batch consistency and purity suitable for research and development applications. Standard quality assurance includes identity confirmation by spectroscopic methods and purity determination by HPLC. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. For projects requiring material under cGMP or other specific regulatory frameworks, please contact us to discuss custom synthesis and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.