Description

7-Trifluoromethyl-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrimidine is a high-value, heterocyclic organic compound featuring a fused pyrazole and pyrimidine ring system substituted with a trifluoromethyl group. This structure is of significant interest in modern organic synthesis, particularly for its role as a versatile pharmaceutical intermediate and a key building block in medicinal chemistry. It is primarily sought after by research institutions and chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Used in the research and development of specialty chemicals, dyes, and advanced polymers.
• Academic & Contract Research: A valuable reagent for synthetic organic chemists in universities and CROs (Contract Research Organizations) exploring novel heterocyclic chemistry and fluorine chemistry.
• Chemical Library Synthesis: Employed in the construction of diverse compound libraries for high-throughput screening in drug discovery programs.

Basic Information

Product Name	7-Trifluoromethyl-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrimidine
CAS No.	725699-19-4
Molecular Formula	C7H7F3N3
Molecular Weight	190.15 g/mol
Synonyms	7-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[1,5-a]pyrimidine; 4,5,6,7-Tetrahydro-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine; 7-Trifluoromethyl-4,5,6,7-tetrahydro-1H-pyrazolo[1,5-a]pyrimidine; 725699-19-4; Pyrazolo[1,5-a]pyrimidine, 4,5,6,7-tetrahydro-7-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of 7-Trifluoromethyl-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrimidine adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity, which is critical for research and scale-up processes. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity (HPLC), identity (IR, NMR), and impurity profiles. Our quality systems are designed to support cGMP compliance for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.