Description

7-(Difluoromethyl)-5-Methyl-4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a defined heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is essential for research and development chemists and manufacturers in the pharmaceutical and agrochemical industries seeking to develop new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of new drug molecules, especially in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.
• Active Pharmaceutical Ingredient (API) Manufacturing: Incorporated into the final synthesis steps of target APIs requiring its specific difluoromethyl-pyrazolopyrimidine core.
• Contract Manufacturing Organizations (CMOs): Supplied to CMOs for custom synthesis and scale-up projects under cGMP conditions.
• Academic & Institutional Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Product Name	7-(Difluoromethyl)-5-Methyl-4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid
CAS No.	725699-03-6
Molecular Formula	C10H11F2N3O2
Molecular Weight	243.21 g/mol
Synonyms	7-(Difluoromethyl)-5-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxylic acid; 4,5,6,7-Tetrahydro-7-(difluoromethyl)-5-methylpyrazolo[1,5-a]pyrimidine-2-carboxylic acid; 725699-03-6; Pyrazolo[1,5-a]pyrimidine-2-carboxylic acid, 4,5,6,7-tetrahydro-7-(difluoromethyl)-5-methyl-; 7-Difluoromethyl-5-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for pharmaceutical intermediates. Each batch is analyzed using advanced techniques like HPLC, GC, and NMR to confirm identity, purity, and the absence of specified impurities. Certificates of Analysis (COA) are available upon request, detailing all critical quality attributes. We support development under quality systems suitable for cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.