Description

n-(2-Fluorobenzyl)-4-Methylaniline is a specialized fluorinated aromatic amine building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and functional materials, where the fluorine atom and aniline moiety impart unique electronic and binding properties. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to innovate new molecular entities.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly in kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorobenzyl group can enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for catalysis and metal-organic frameworks (MOFs) due to its chelating amine functionality.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of advanced polymers, liquid crystals, and electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorescent tags, photoaffinity labels, and other molecular probes for biological research.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	n-(2-Fluorobenzyl)-4-Methylaniline
CAS No.	723753-88-6
Molecular Formula	C14H14FN
Molecular Weight	215.27 g/mol
Synonyms	4-Methyl-N-[(2-fluorophenyl)methyl]aniline; N-(2-Fluorobenzyl)-p-toluidine; 1-(2-Fluorophenyl)-N-(4-methylphenyl)methanamine; Benzenemethanamine, 2-fluoro-N-(4-methylphenyl)-; 2-Fluoro-N-(4-methylbenzyl)aniline; N-(4-Methylphenyl)-1-(2-fluorophenyl)methanamine; (2-Fluorobenzyl)(4-methylphenyl)amine
EINECS	Contact for details

Quality Control

Our n-(2-Fluorobenzyl)-4-Methylaniline is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot undergoes comprehensive analytical characterization, including HPLC, GC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) specifying identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Light yellow to brown solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.