Description

Ethyl 7-(4-Methylphenyl)-5-Phenyl-4,7-Dihydro[1,2,4]Triazolo[1,5-A]Pyrimidine-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the fused triazolopyrimidine class of heterocyclic compounds. Its complex molecular architecture makes it a critical building block for the research and development of novel active pharmaceutical ingredients (APIs). This compound is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in synthesizing targeted therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory conditions, and oncology.
• Organic Synthesis Building Block: Used in research-scale and process chemistry for constructing complex nitrogen-containing heterocycles due to its reactive ester and triazolopyrimidine functionalities.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs to develop new chemical entities with enhanced biological activity.
• Agrochemical Development: Potential application as an intermediate in the research of new pesticides and herbicides, leveraging its heterocyclic core.
• Academic & Institutional Research: Used in universities and research institutes for methodological studies in heterocyclic chemistry and the development of new synthetic pathways.

Basic Information

Item	Detail
Product Name	Ethyl 7-(4-Methylphenyl)-5-Phenyl-4,7-Dihydro[1,2,4]Triazolo[1,5-A]Pyrimidine-6-Carboxylate
CAS No.	722462-65-9
Molecular Formula	C22H20N4O2
Molecular Weight	372.42 g/mol
Synonyms	Ethyl 7-(p-tolyl)-5-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate; 7-(4-Methylphenyl)-5-phenyl-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester; 722462-65-9; Ethyl 5-phenyl-7-(4-methylphenyl)-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate; [1,2,4]Triazolo[1,5-a]pyrimidine-6-carboxylic acid, 4,7-dihydro-7-(4-methylphenyl)-5-phenyl-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 7-(4-Methylphenyl)-5-Phenyl-4,7-Dihydro[1,2,4]Triazolo[1,5-A]Pyrimidine-6-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.