Description

5-Bromo-N4-(Pyridin-2-Yl)-N2-(3-(1,2,3,6-Tetrahydropyridin-4-Yl)-1H-Indol-5-Yl)Pyrimidine-2,4-Diamine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the research and development of novel therapeutic agents, particularly kinase inhibitors. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and contract research organizations (CROs) focused on oncology, neurology, and inflammatory disease pathways.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of targeted small-molecule drugs, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel drug candidates.
• Biochemical Assay Development: Serves as a reference standard or probe compound in high-throughput screening and enzymatic assays.
• Oncology Drug Discovery: Investigated for its potential in modulating specific signaling pathways relevant to cancer cell proliferation.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and chemical biology.
• Custom Synthesis: A starting material for the contract manufacturing of more complex, proprietary active pharmaceutical ingredients (APIs).

Basic Information

Product Name	5-Bromo-N4-(Pyridin-2-Yl)-N2-(3-(1,2,3,6-Tetrahydropyridin-4-Yl)-1H-Indol-5-Yl)Pyrimidine-2,4-Diamine
CAS No.	719312-02-4
Molecular Formula	C22H21BrN8
Molecular Weight	477.36 g/mol
Synonyms	5-Bromo-N4-(2-pyridinyl)-N2-[3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indol-5-yl]-2,4-pyrimidinediamine; 5-Bromo-N4-(pyridin-2-yl)-N2-[3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indol-5-yl]pyrimidine-2,4-diamine; 2,4-Pyrimidinediamine, 5-bromo-N4-(2-pyridinyl)-N2-[3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indol-5-yl]-; CAS 719312-02-4
EINECS	Contact for details

Quality Control

Our 5-Bromo-N4-(Pyridin-2-Yl)-N2-(3-(1,2,3,6-Tetrahydropyridin-4-Yl)-1H-Indol-5-Yl)Pyrimidine-2,4-Diamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. The compound is light-sensitive and should be handled under inert atmosphere when appropriate for long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.