Description

4-(2-Cyano-3-Fluorophenyl)Benzaldehyde is a high-purity, multi-functional aromatic aldehyde building block. This compound is valued for its unique molecular architecture, combining a benzaldehyde core with cyano and fluoro substituents, which imparts specific electronic and steric properties for advanced synthesis. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical sectors for the construction of complex molecules, including potential active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge-transport molecules.
• Fluorescent Probe and Dye Chemistry: Acts as a starting material for synthesizing fluorophores and molecular sensors due to its modifiable aldehyde and aromatic groups.
• Custom Chemical Synthesis: Provides a critical building block for contract research organizations (CROs) and custom synthesis houses serving diverse R&D projects.

Basic Information

Product Name	4-(2-Cyano-3-Fluorophenyl)Benzaldehyde
CAS No.	718628-28-5
Molecular Formula	C14H8FNO
Molecular Weight	225.22 g/mol
Synonyms	4-(2-Cyano-3-fluorophenyl)benzaldehyde; [1,1'-Biphenyl]-4-carboxaldehyde, 2'-cyano-3'-fluoro-; 2'-Cyano-3'-fluoro[1,1'-biphenyl]-4-carboxaldehyde; 3-Fluoro-2-cyanobiphenyl-4-carboxaldehyde; 4-(2-Cyano-3-fluorophenyl)benzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of 4-(2-Cyano-3-Fluorophenyl)Benzaldehyde is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive R&D and scale-up applications. A detailed Certificate of Analysis (COA) including HPLC purity, identity confirmation (IR, NMR), and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.