Description

Boc-D-β-Homoser(Bzl)-Oh is a protected, non-proteinogenic amino acid derivative widely used as a key chiral building block in advanced organic synthesis. This high-purity intermediate is essential for constructing complex peptide and peptidomimetic structures with specific stereochemistry. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of novel therapeutic agents and bioactive compounds.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptidomimetic Research: Used in medicinal chemistry to design and synthesize peptidomimetics with enhanced metabolic stability and bioavailability.
• Solid-Phase Peptide Synthesis (SPPS): Serves as a protected amino acid derivative for the sequential assembly of custom peptides on resin.
• Bioconjugation & Probe Development: Facilitates the site-specific incorporation of homoserine derivatives into biomolecules for labeling and diagnostic applications.
• Chemical Biology Tool: Enables the study of protein structure-function relationships by introducing non-natural amino acids.
• Academic & Industrial R&D: A valuable reagent for research laboratories focused on organic methodology and new compound library generation.

Basic Information

Product Name	Boc-D-β-Homoser(Bzl)-Oh
CAS No.	718608-08-3
Molecular Formula	C16H23NO5
Molecular Weight	309.36 g/mol
Synonyms	(R)-2-((tert-Butoxycarbonyl)amino)-4-(benzyloxy)butanoic acid; Boc-D-β-Homoserine(Bzl)-OH; Boc-D-Homoser(Bzl)-OH; N-(tert-Butoxycarbonyl)-D-β-homoserine benzyl ether; D-2-Amino-4-(benzyloxy)butyric acid N-Boc derivative; Boc-D-Hse(Bzl)-OH; N-Boc-D-β-homoserine benzyl ester (acid form); (R)-2-(Boc-amino)-4-(benzyloxy)butanoic acid
EINECS	Contact for details

Quality Control

Our Boc-D-β-Homoser(Bzl)-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.