Description

tert-Butyl 4-(4-Chloro-7H-Pyrrolo[2,3-D]Pyrimidin-7-Yl)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant importance in modern drug discovery. This compound serves as a critical building block for the synthesis of targeted kinase inhibitors, enabling the development of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of oncology and immunology treatments.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the development of small molecule kinase inhibitors targeting various cancer pathways.
• Oncology Drug Discovery: Used in the research and synthesis of potential therapeutic compounds for treating specific types of tumors and hematological malignancies.
• Biochemical Research: Serves as a tool compound in enzymatic assays and structure-activity relationship (SAR) studies to understand kinase function and inhibition.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and the cGMP-compliant manufacturing of active pharmaceutical ingredients (APIs).
• Custom Synthesis: Building block for the preparation of more complex, proprietary molecules in medicinal chemistry programs.

Basic Information

Product Name	tert-Butyl 4-(4-Chloro-7H-Pyrrolo[2,3-D]Pyrimidin-7-Yl)Piperidine-1-Carboxylate
CAS No.	717900-74-8
Molecular Formula	C16H19ClN4O2
Molecular Weight	334.80 g/mol
Synonyms	1-Boc-4-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)piperidine; 4-(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl 4-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)piperidine-1-carboxylate; 7-[1-(tert-Butoxycarbonyl)piperidin-4-yl]-4-chloro-7H-pyrrolo[2,3-d]pyrimidine; BOC-4-(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(4-Chloro-7H-Pyrrolo[2,3-D]Pyrimidin-7-Yl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.