Description

N~2~-(4-Methoxyphenyl)-6-(3-Methylpiperidin-1-Yl)-5-Nitropyrimidine-2,4-Diamine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of potential drug candidates, especially for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new chemical entities.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for pilot and commercial manufacturing.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in API production.
• Biochemical Tool Compound: May be utilized in biochemical assays to study specific enzyme interactions and pathways.

Basic Information

Product Name	N~2~-(4-Methoxyphenyl)-6-(3-Methylpiperidin-1-Yl)-5-Nitropyrimidine-2,4-Diamine
CAS No.	716341-75-2
Molecular Formula	C17H22N6O3
Molecular Weight	358.40 g/mol
Synonyms	2-N-(4-Methoxyphenyl)-6-(3-methyl-1-piperidinyl)-5-nitro-2,4-pyrimidinediamine; 6-(3-Methylpiperidin-1-yl)-N2-(4-methoxyphenyl)-5-nitropyrimidine-2,4-diamine; 5-Nitro-6-(3-methylpiperidin-1-yl)-N2-(4-methoxyphenyl)pyrimidine-2,4-diamine; 716341-75-2; UNII-8V1F4S5W4K; 8V1F4S5W4K
EINECS	Contact for details

Quality Control

Our N~2~-(4-Methoxyphenyl)-6-(3-Methylpiperidin-1-Yl)-5-Nitropyrimidine-2,4-Diamine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and regulatory support.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.