Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-7-[4-[[(2-Fluorophenyl)Amino]Thioxomethyl]-3-Methyl-1-Piperazinyl]-1,4-Dihydro-8-Methoxy-4-Oxo- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of critical importance for the synthesis of novel fluoroquinolone antibiotics, offering a key building block for research and development in antimicrobial therapies. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on developing next-generation antibacterial agents.

Application

• Key Intermediate in Fluoroquinolone Antibiotic Synthesis: Serves as a crucial precursor in the production of advanced, broad-spectrum antibacterial agents.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the design and synthesis of new drug candidates targeting bacterial infections.
• Process Chemistry & Scale-Up: Employed in optimizing synthetic routes and scaling up production for clinical trial material (CTM) and commercial Active Pharmaceutical Ingredient (API) manufacturing.
• Academic & Institutional Research: Utilized in universities and research institutes for studying structure-activity relationships (SAR) and mechanisms of action in antibacterial compounds.
• Fine Chemical Production: Supplied to fine chemical companies for further functionalization and integration into complex molecular architectures.

Basic Information

Item	Details
Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-7-[4-[[(2-Fluorophenyl)Amino]Thioxomethyl]-3-Methyl-1-Piperazinyl]-1,4-Dihydro-8-Methoxy-4-Oxo-
CAS No.	716333-90-3
Molecular Formula	C25H25F2N4O3S
Molecular Weight	499.56 g/mol
Synonyms	1-Cyclopropyl-6-fluoro-7-[4-[[(2-fluorophenyl)amino]thioxomethyl]-3-methyl-1-piperazinyl]-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid; 3-Quinolinecarboxylic acid, 1,4-dihydro-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-7-[4-[[(2-fluorophenyl)amino]thioxomethyl]-3-methyl-1-piperazinyl]-; Intermediate for advanced fluoroquinolones; Gatifloxacin related intermediate; Fluoroquinolone piperazinyl derivative.
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.