Description

N~2~-(4-Chlorophenyl)-N~4~-(4-Fluorophenyl)-5-Nitropyrimidine-2,4,6-Triamine is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated aromatic and nitropyrimidine structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel drug candidates. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing targeted therapies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted small-molecule drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize biological activity by modifying the pyrimidine core.
• Biochemical Tool Compound: Serves as a precursor or reference standard in biochemical assays and pharmacological profiling.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex, nitrogen-containing heterocycles with specific substitution patterns.
• Agrochemical Research: Investigated as an intermediate for developing new herbicides or fungicides, leveraging its nitropyrimidine scaffold.

Basic Information

Product Name	N~2~-(4-Chlorophenyl)-N~4~-(4-Fluorophenyl)-5-Nitropyrimidine-2,4,6-Triamine
CAS No.	716332-14-8
Molecular Formula	C16H12ClFN6O2
Molecular Weight	374.76 g/mol
Synonyms	2,4,6-Triamino-5-nitro-N2-(4-chlorophenyl)-N4-(4-fluorophenyl)pyrimidine; 5-Nitro-N2-(4-chlorophenyl)-N4-(4-fluorophenyl)-2,4,6-pyrimidinetriamine; N2-(4-Chlorophenyl)-N4-(4-fluorophenyl)-5-nitropyrimidine-2,4,6-triamine; 716332-14-8; 4-Chloro-N-[4-(4-fluorophenyl)amino]-5-nitro-2-pyrimidinyl]aniline; 2,4,6-Triamino-5-nitro-N-(4-chlorophenyl)-N'-(4-fluorophenyl)pyrimidine
EINECS	Contact for details

Quality Control

Our N~2~-(4-Chlorophenyl)-N~4~-(4-Fluorophenyl)-5-Nitropyrimidine-2,4,6-Triamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.