Description

N⁴-(3,4-Dimethylphenyl)-N²-(2-Fluorophenyl)-5-Nitropyrimidine-2,4,6-Triamine is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel drug candidates targeting specific biological pathways. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug discovery programs.
• Chemical Biology Probe: Serves as a core scaffold for developing molecular probes to study enzyme function and cellular signaling pathways.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex, nitrogen-containing heterocycles with specific substitution patterns.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	N⁴-(3,4-Dimethylphenyl)-N²-(2-Fluorophenyl)-5-Nitropyrimidine-2,4,6-Triamine
CAS No.	714948-20-6
Molecular Formula	C₁₈H₁₇FN₆O₂
Molecular Weight	368.37 g/mol
Synonyms	5-Nitro-N⁴-(3,4-dimethylphenyl)-N²-(2-fluorophenyl)-2,4,6-pyrimidinetriamine; 2,4,6-Triamino-5-nitro-N⁴-(3,4-dimethylphenyl)-N²-(2-fluorophenyl)pyrimidine; N2-(2-Fluorophenyl)-N4-(3,4-dimethylphenyl)-5-nitropyrimidine-2,4,6-triamine; 714948-20-6; 5-Nitropyrimidine-2,4,6-triamine, N⁴-(3,4-dimethylphenyl)-N²-(2-fluorophenyl)-; (2-Fluorophenyl)-[6-amino-5-nitro-4-[(3,4-dimethylphenyl)amino]pyrimidin-2-yl]amine
EINECS	Contact for details

Quality Control

Our production of N⁴-(3,4-Dimethylphenyl)-N²-(2-Fluorophenyl)-5-Nitropyrimidine-2,4,6-Triamine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere); prolonged exposure to air, light, or moisture should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.