Description

N~2~-(3-Chlorophenyl)-5-Nitro-6-(Pyrrolidin-1-Yl)Pyrimidine-2,4-Diamine is a high-purity, advanced pharmaceutical intermediate designed for research and development. This compound is critical for medicinal chemistry programs, particularly in the synthesis of novel small-molecule drug candidates targeting a range of therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions engaged in the development of new active pharmaceutical ingredients (APIs).

Application

This specialized pyrimidine derivative serves as a key building block in sophisticated chemical synthesis. Its primary applications include:

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in oncology and antiviral research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery pipelines.
• Chemical Biology Probe Development: Serves as a core scaffold for creating molecular probes to study biological pathways and protein functions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and drug design.

Basic Information

Product Name	N~2~-(3-Chlorophenyl)-5-Nitro-6-(Pyrrolidin-1-Yl)Pyrimidine-2,4-Diamine
CAS No.	714918-12-4
Molecular Formula	C14H15ClN6O2
Molecular Weight	334.76 g/mol
Synonyms	2,4-Pyrimidinediamine, N2-(3-chlorophenyl)-5-nitro-6-(1-pyrrolidinyl)-; 2-Amino-4-[(3-chlorophenyl)amino]-5-nitro-6-(pyrrolidin-1-yl)pyrimidine; 5-Nitro-6-(pyrrolidin-1-yl)-N2-(3-chlorophenyl)pyrimidine-2,4-diamine; 714918-12-4; N2-(3-Chlorophenyl)-5-nitro-6-(pyrrolidin-1-yl)pyrimidine-2,4-diamine
EINECS	Contact for details

Quality Control

Our N~2~-(3-Chlorophenyl)-5-Nitro-6-(Pyrrolidin-1-Yl)Pyrimidine-2,4-Diamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be stored away from direct light exposure. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.