Description

6-(4-Ethylpiperazin-1-Yl)-N~2~-(4-Methylphenyl)-5-Nitropyrimidine-2,4-Diamine is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting specific biological pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of potential new drug candidates, particularly in oncology and CNS-related therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop molecules with improved efficacy and safety profiles.
• Chemical Reference Standard: Serves as a high-purity analytical standard for method development, validation, and quality control in API manufacturing.
• Biochemical Research: Employed in biochemical assays and as a tool compound for investigating enzyme inhibition and receptor binding activities.
• Custom Synthesis: A starting material for the contract synthesis of specialized, non-commercially available chemical entities for client-specific research programs.

Basic Information

Item	Details
Product Name	6-(4-Ethylpiperazin-1-Yl)-N~2~-(4-Methylphenyl)-5-Nitropyrimidine-2,4-Diamine
CAS No.	714286-12-1
Molecular Formula	C17H24N8O2
Molecular Weight	372.43 g/mol
Synonyms	6-(4-Ethyl-1-piperazinyl)-N2-(4-methylphenyl)-5-nitro-2,4-pyrimidinediamine; 5-Nitro-6-(4-ethyl-1-piperazinyl)-N2-(4-methylphenyl)-2,4-pyrimidinediamine; 6-(4-Ethylpiperazin-1-yl)-N2-(p-tolyl)-5-nitropyrimidine-2,4-diamine; 714286-12-1; 6-(4-Ethylpiperazin-1-yl)-N2-(4-methylphenyl)-5-nitropyrimidine-2,4-diamine; 6-(4-Ethylpiperazin-1-yl)-N2-(p-tolyl)-5-nitropyrimidine-2,4-diamine
EINECS	Contact for details

Quality Control

Our 6-(4-Ethylpiperazin-1-Yl)-N~2~-(4-Methylphenyl)-5-Nitropyrimidine-2,4-Diamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation (by IR, NMR, and MS), and impurity profile is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.