Description

2-{[(4-Chlorophenyl)Methyl]Amino}-6-Methyl-3,4-Dihydropyrimidin-4-One is a high-purity, synthetically derived dihydropyrimidinone derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in providing a structurally defined scaffold for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and specialty fine chemical industries seeking reliable, high-quality building blocks.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, or metabolic conditions.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, or insecticides with optimized efficacy and environmental profiles.
• Chemical Biology Probe: Serves as a core structure for creating molecular probes to study enzyme function or protein-ligand interactions in biological systems.
• Material Science Research: Potential intermediate for synthesizing specialty polymers or organic electronic materials with specific functional properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific synthesis projects requiring this precise molecular framework.
• Academic & Institutional R&D: Used in university and government laboratories for methodological studies in heterocyclic chemistry and medicinal chemistry programs.

Basic Information

Product Name	2-{[(4-Chlorophenyl)Methyl]Amino}-6-Methyl-3,4-Dihydropyrimidin-4-One
CAS No.	714214-12-7
Molecular Formula	C12H12ClN3O
Molecular Weight	249.70 g/mol
Synonyms	2-[(4-Chlorobenzyl)amino]-6-methyl-3,4-dihydropyrimidin-4-one; 6-Methyl-2-[[(4-chlorophenyl)methyl]amino]-3,4-dihydro-4-pyrimidinone; 4(1H)-Pyrimidinone, 2-[[(4-chlorophenyl)methyl]amino]-3,4-dihydro-6-methyl-; 2-((4-Chlorobenzyl)amino)-6-methyl-3,4-dihydropyrimidin-4(1H)-one; 714214-12-7; 2-[(4-Chlorobenzyl)amino]-6-methylpyrimidin-4(3H)-one (tautomeric form)
EINECS	Contact for details

Quality Control

Our 2-{[(4-Chlorophenyl)Methyl]Amino}-6-Methyl-3,4-Dihydropyrimidin-4-One is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) documenting all specifications are provided to ensure traceability and compliance with your internal quality standards and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.