Description

2-Amino-4-(3,4-Difluorophenyl)-5H-Indeno[1,2-D]Pyrimidin-5-One is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrimidine class of heterocyclic compounds. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Kinase Inhibitor Scaffold: Serves as a core structural motif for designing and synthesizing potential tyrosine kinase and serine/threonine kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize potency and selectivity of drug candidates.
• Biochemical Probe Development: Employed in the creation of tool compounds for studying specific enzymatic pathways and cellular processes.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2-Amino-4-(3,4-Difluorophenyl)-5H-Indeno[1,2-D]Pyrimidin-5-One
CAS No.	713514-76-2
Molecular Formula	C17H10F2N4O
Molecular Weight	324.28 g/mol
Synonyms	2-Amino-4-(3,4-difluorophenyl)indeno[1,2-d]pyrimidin-5-one; 5H-Indeno[1,2-d]pyrimidin-5-one, 2-amino-4-(3,4-difluorophenyl)-; 713514-76-2; 2-Amino-4-(3,4-difluorophenyl)-5H-indeno[1,2-d]pyrimidin-5-one; 4-(3,4-Difluorophenyl)-2-amino-5H-indeno[1,2-d]pyrimidin-5-one; Indeno[1,2-d]pyrimidine derivative; Fused pyrimidine intermediate
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(3,4-Difluorophenyl)-5H-Indeno[1,2-D]Pyrimidin-5-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.