Description

N⁴-(4-Fluorophenyl)-N²-(3-Methoxyphenyl)-5-Nitropyrimidine-2,4,6-Triamine is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel drug candidates targeting specific biological pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug molecules, especially in oncology and targeted therapy research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the efficacy and selectivity of lead compounds.
• Kinase Inhibitor Development: A valuable precursor in the research and development of kinase inhibitors due to its pyrimidine-triamine core.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme interactions and cellular signaling mechanisms.
• Custom Synthesis: Used by fine chemical suppliers for the custom synthesis of complex, high-value molecules for client-specific projects.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	N⁴-(4-Fluorophenyl)-N²-(3-Methoxyphenyl)-5-Nitropyrimidine-2,4,6-Triamine
CAS No.	713086-76-1
Molecular Formula	C₁₇H₁₅FN₆O₃
Molecular Weight	370.34 g/mol
Synonyms	5-Nitro-N2-(3-methoxyphenyl)-N4-(4-fluorophenyl)pyrimidine-2,4,6-triamine; 2,4,6-Pyrimidinetriamine, N4-(4-fluorophenyl)-N2-(3-methoxyphenyl)-5-nitro-; N2-(3-Methoxyphenyl)-N4-(4-fluorophenyl)-5-nitropyrimidine-2,4,6-triamine; 713086-76-1; 5-Nitro-N2-(3-methoxyphenyl)-N4-(4-fluorophenyl)-2,4-pyrimidinediamine; SCHEMBL21806227; AKOS040759623; A1-00823
EINECS	Contact for details

Quality Control

Our N⁴-(4-Fluorophenyl)-N²-(3-Methoxyphenyl)-5-Nitropyrimidine-2,4,6-Triamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (HPLC), related substances, and residual solvents. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.