Description

Ethyl 4-(4-Fluorophenyl)-6-Isopropyl-2-Amino-Pyrimidine-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its specific pyrimidine core structure. This compound is critical for ensuring the quality and efficacy of downstream active pharmaceutical ingredients (APIs), particularly in the synthesis of complex therapeutic agents. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Serves as a precursor in the development of new-generation herbicides and fungicides with enhanced activity and selectivity.
• Chemical Synthesis: Used in organic synthesis for constructing complex heterocyclic frameworks in medicinal chemistry programs.
• Academic & R&D: Employed in university and corporate research laboratories for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	Ethyl 4-(4-Fluorophenyl)-6-Isopropyl-2-Amino-Pyrimidine-5-Carboxylate
CAS No.	712320-67-7
Molecular Formula	C16H18FN3O2
Molecular Weight	303.33 g/mol
Synonyms	Ethyl 2-Amino-4-(4-fluorophenyl)-6-(propan-2-yl)pyrimidine-5-carboxylate; 5-Pyrimidinecarboxylic acid, 2-amino-4-(4-fluorophenyl)-6-(1-methylethyl)-, ethyl ester; 4-(4-Fluorophenyl)-6-isopropyl-2-aminopyrimidine-5-carboxylic acid ethyl ester; 2-Amino-4-(p-fluorophenyl)-6-isopropyl-5-pyrimidinecarboxylic acid ethyl ester; Ethyl 2-amino-4-(4-fluorophenyl)-6-isopropylpyrimidine-5-carboxylate; 712320-67-7
EINECS	Contact for details

Quality Control

Our production of Ethyl 4-(4-Fluorophenyl)-6-Isopropyl-2-Amino-Pyrimidine-5-Carboxylate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality system is designed to support cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.