Description

(R)-n-(1-(3-Benzyl-7-Chloro-4-Oxo-3,4-Dihydroquinazolin-2-Yl)Propyl)-4-Bromo-n-(3-(Dimethylamino)Propyl)Benzamide is a sophisticated, high-purity organic compound designed for advanced research and development. This molecule is a critical building block in medicinal chemistry, valued for its complex heterocyclic structure and chiral center which enable precise biological targeting. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents, particularly for applications in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for targeted therapies.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Kinase Inhibitor Development: Serves as a valuable building block in the synthesis of potential quinazolinone-based kinase inhibitors for oncology research.
• Preclinical Candidate Synthesis: Employed in the gram-to-kilogram scale synthesis of lead compounds for pharmacological evaluation and preclinical studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized, non-commercial compounds under cGMP guidelines.
• Academic Research: Utilized in university and institutional labs for cutting-edge research in organic synthesis methodology and drug discovery.

Basic Information

Product Name	(R)-n-(1-(3-Benzyl-7-Chloro-4-Oxo-3,4-Dihydroquinazolin-2-Yl)Propyl)-4-Bromo-n-(3-(Dimethylamino)Propyl)Benzamide
CAS No.	709039-94-1
Molecular Formula	C30H32BrClN4O2
Molecular Weight	596.0 g/mol
Synonyms	(R)-N-[1-(3-Benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)propyl]-4-bromo-N-[3-(dimethylamino)propyl]benzamide; 4-Bromo-N-[3-(dimethylamino)propyl]-N-[(1R)-1-[3-(phenylmethyl)-7-chloro-4-oxo-3H-quinazolin-2-yl]propyl]benzamide; UNII-9Q3Q5P5T8Y; Benzamide, 4-bromo-N-[3-(dimethylamino)propyl]-N-[(1R)-1-[3-(phenylmethyl)-7-chloro-4-oxo-3H-quinazolin-2-yl]propyl]-; (R)-enantiomer of a quinazolinone benzamide derivative
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and analyzed under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles to ensure it meets the exacting standards required for pharmaceutical R&D. Our quality protocols are designed to support development under cGMP (current Good Manufacturing Practice) guidelines where applicable, ensuring traceability, consistency, and reliability for your critical research programs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. The compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged manipulation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.