Description

1-[3-(Trifluoromethyl)Phenyl]Butan-1-Amine is a specialized aromatic amine derivative featuring a trifluoromethyl substituent, a structural motif of significant interest in advanced chemical synthesis. This compound matters as a versatile and high-value building block, prized for its ability to impart unique physicochemical properties, such as enhanced lipophilicity and metabolic stability, into target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by manufacturers of specialty materials and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized in the design and creation of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production for clients in fine chemical sectors.

Basic Information

Product Name	1-[3-(Trifluoromethyl)Phenyl]Butan-1-Amine
CAS No.	708253-40-1
Molecular Formula	C11H14F3N
Molecular Weight	217.23 g/mol
Synonyms	1-(3-(Trifluoromethyl)phenyl)butan-1-amine; 3'-(Trifluoromethyl)butyrophenone imine (reduction precursor); α-Methyl-3-(trifluoromethyl)benzenepropanamine; 1-Butanamine, 1-[3-(trifluoromethyl)phenyl]-; 3-Trifluoromethylphenylbutylamine; 1-(3-Trifluoromethylphenyl)butylamine; Benzenepropanamine, α-methyl-3-(trifluoromethyl)-; 3-(Trifluoromethyl)hydratropamine
EINECS	Contact for details

Quality Control

Our 1-[3-(Trifluoromethyl)Phenyl]Butan-1-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual ≤ 0.5%, Total ≤ 1.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.