Description

2-[[6-Amino-3-(Phenylmethyl)-3H-Purin-8-Yl]Thio]Acetic Acid is a high-purity, specialized purine derivative that serves as a critical building block in advanced pharmaceutical and biochemical research. This compound is valued for its role as a key intermediate in the synthesis of novel therapeutic agents, particularly those targeting specific enzymatic pathways. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the creation of innovative drug candidates and biochemical probes.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel adenosine receptor modulators and other purine-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate purine metabolism and related cellular signaling pathways.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies in drug discovery programs targeting inflammation, cancer, and neurological disorders.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Fine Chemical Synthesis: Acts as a specialized building block for constructing complex molecules with potential biological activity in custom synthesis projects.

Basic Information

Product Name	2-[[6-Amino-3-(Phenylmethyl)-3H-Purin-8-Yl]Thio]Acetic Acid
CAS No.	708218-22-8
Molecular Formula	C₁₄H₁₃N₅O₂S
Molecular Weight	315.35 g/mol
Synonyms	8-Mercaptoadenosine Benzyl Derivative; 2-[(6-Amino-3-benzyl-3H-purin-8-yl)thio]acetic Acid; 8-Thio-6-aminopurine Acetic Acid Benzyl Derivative; NSC 760463; 3-Benzyl-6-amino-8-mercaptopurine-2-acetic Acid; 8-Sulfanyl-3-benzyl-3H-purin-6-amine Acetic Acid Ester
EINECS	Contact for details

Quality Control

Our production of 2-[[6-Amino-3-(Phenylmethyl)-3H-Purin-8-Yl]Thio]Acetic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for research and development applications. All material is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.