Description

2-(4-Amino-2-Oxo-1(2H)-Pyrimidinyl)-1,5-Anhydro-2-Deoxy-4,6-o-[(R)-Phenylmethylene]-D-Altritol is a sophisticated nucleoside analogue derivative, serving as a critical building block in advanced pharmaceutical research and development. Its unique chemical structure, featuring a protected altritol sugar moiety, makes it a valuable intermediate for the synthesis of novel antiviral and anticancer agents, particularly in the development of modified nucleoside therapeutics. This high-purity compound is essential for medicinal chemists and researchers in pharmaceutical, biotechnology, and fine chemical industries focused on creating next-generation therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel nucleoside-based antiviral drugs.
• Anticancer Agent Research: Used in the synthesis of potential chemotherapeutic compounds targeting DNA/RNA synthesis.
• Medicinal Chemistry: Serves as a crucial building block for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Research: Employed in studies involving enzyme inhibition, particularly those related to viral polymerases.
• Process Development: Utilized in scaling up synthetic routes for active pharmaceutical ingredients (APIs) in GMP environments.
• Fine Chemical Synthesis: An advanced intermediate for creating specialized, high-value chiral compounds.

Basic Information

Product Name	2-(4-Amino-2-Oxo-1(2H)-Pyrimidinyl)-1,5-Anhydro-2-Deoxy-4,6-o-[(R)-Phenylmethylene]-D-Altritol
CAS No.	705967-79-9
Molecular Formula	C₁₈H₂₁N₃O₆
Molecular Weight	375.38 g/mol
Synonyms	4-Amino-1-((2R,3R,4R,5R)-3,4-Bis((R)-phenylmethylidene)oxy)-5-(hydroxymethyl)oxolan-2-yl)pyrimidin-2(1H)-one; D-Altritol, 2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,5-anhydro-2-deoxy-4,6-O-[(R)-phenylmethylene]-; Protected Cytidine Altritol Derivative; Nucleoside Altritol Intermediate; Benzylidene-protected Altritol Cytosine
EINECS	Contact for details

Quality Control

Our 2-(4-Amino-2-Oxo-1(2H)-Pyrimidinyl)-1,5-Anhydro-2-Deoxy-4,6-o-[(R)-Phenylmethylene]-D-Altritol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and comprehensive identification tests. We provide full traceability and detailed Certificates of Analysis (COA) to support your regulatory and R&D requirements. Specifications are designed to meet the stringent needs of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.