Description

Pyrido[3,4-D]Pyrimidin-4(3H)-One, 6-Chloro-2-(1,1-Dimethylethyl)- is a high-value heterocyclic building block of significant interest in advanced organic synthesis. This compound is critical for research and development in the pharmaceutical and agrochemical sectors, where its unique pyridopyrimidine core serves as a privileged scaffold. It is primarily sought after by medicinal chemists and process development scientists for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies for drug discovery programs.
• Agrochemical Development: Serves as a precursor in the synthesis of novel herbicides, fungicides, or plant growth regulators.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme function and biological pathways.
• Fine Chemical Synthesis: Intermediate for the production of complex, high-value specialty chemicals.

Basic Information

Product Name	Pyrido[3,4-D]Pyrimidin-4(3H)-One, 6-Chloro-2-(1,1-Dimethylethyl)-
CAS No.	705291-51-6
Molecular Formula	C11H12ClN3O
Molecular Weight	237.69 g/mol
Synonyms	6-Chloro-2-tert-butylpyrido[3,4-d]pyrimidin-4(3H)-one; 2-tert-Butyl-6-chloro-3,4-dihydro-4-pyrido[3,4-d]pyrimidinone; 6-Chloro-2-(tert-butyl)pyrido[3,4-d]pyrimidin-4(3H)-one; 6-Chloro-2-(1,1-dimethylethyl)-3,4-dihydropyrido[3,4-d]pyrimidin-4-one; 6-Chloro-2-tert-butyl-3H-pyrido[3,4-d]pyrimidin-4-one; 705291-51-6; tert-Butyl 6-chloro-4-oxo-3,4-dihydropyrido[3,4-d]pyrimidin-2-yl
EINECS	Contact for details

Quality Control

Our Pyrido[3,4-D]Pyrimidin-4(3H)-One, 6-Chloro-2-(1,1-Dimethylethyl)- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support development and commercial projects with material that meets rigorous in-house specifications and can provide custom synthesis to meet specific client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.