Description

4,5-Difluoro-2-Methylphenol is a fluorinated phenolic compound that serves as a versatile and critical building block in advanced organic synthesis. Its unique substitution pattern, featuring two fluorine atoms and a methyl group on the phenol ring, makes it a valuable intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients, as well as in materials science for specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity, metabolic stability, and lipophilicity.
• Liquid Crystal Materials: Serves as a core component in the synthesis of fluorinated liquid crystals for high-performance displays (LCDs) due to its ability to modify dielectric anisotropy and viscosity.
• Polymer & Resin Modifier: Incorporated into specialty polymers, epoxy resins, and polycarbonates to improve thermal stability, chemical resistance, and flame retardancy.
• Organic Electronic Materials: Intermediate in the development of organic semiconductors, OLED materials, and charge-transport layers.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in medicinal chemistry, fluorochemistry, and materials science.

Basic Information

Product Name	4,5-Difluoro-2-Methylphenol
CAS No.	704884-76-4
Molecular Formula	C7H6F2O
Molecular Weight	144.12 g/mol
Synonyms	2-Methyl-4,5-difluorophenol; 4,5-Difluoro-o-cresol; 2-Methyl-4,5-difluorophenol; 4,5-Difluoro-2-methylphenol; Phenol, 4,5-difluoro-2-methyl-; 4,5-Difluoro-2-cresol; 2-Hydroxy-3,4-difluorotoluene
EINECS	Contact for details

Quality Control

Our 4,5-Difluoro-2-Methylphenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of our global clientele in research and production. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure full traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.