Description

Ethyl 7-Amino-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its fused heterocyclic structure containing both triazole and pyrimidine rings. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in oncology, antiviral, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced fungicides and herbicides, leveraging its heterocyclic core for bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold in academic and industrial R&D for exploring new chemical entities and structure-activity relationships (SAR).
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the scalable synthesis of final drug substances requiring the [1,2,4]triazolo[1,5-a]pyrimidine pharmacophore.
• Process Chemistry: Utilized in route scouting and optimization for the efficient, cost-effective production of complex target molecules.

Basic Information

Item	Detail
Product Name	Ethyl 7-Amino-2-(Trifluoromethyl)[1,2,4]Triazolo[1,5-A]Pyrimidine-6-Carboxylate
CAS No.	704877-28-1
Molecular Formula	C9H7F3N6O2
Molecular Weight	288.19 g/mol
Synonyms	7-Amino-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester; Ethyl 7-amino-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate; 704877-28-1; 6-Carbethoxy-7-amino-2-trifluoromethyl[1,2,4]triazolo[1,5-a]pyrimidine; [1,2,4]Triazolo[1,5-a]pyrimidine-6-carboxylic acid, 7-amino-2-(trifluoromethyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 7-Amino-2-(Trifluoromethyl)[1,2,4]Triazolo[1,5-A]Pyrimidine-6-Carboxylate is manufactured under strict quality management systems. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents. For long-term storage, consider conditions under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.