Description

2-Iodo-5-(Trifluoromethyl)Benzyl Alcohol is a versatile halogenated benzyl alcohol derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both an iodine substituent and a trifluoromethyl group, makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of compounds targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Research: Used in the discovery and synthesis of novel herbicides and fungicides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of advanced functional materials for electronic displays, leveraging its halogenated aromatic core.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex biaryl structures.
• Ligand & Catalyst Development: Utilized in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Building Block: The presence of the CF3 group makes it a valuable starting material for introducing fluorine into target molecules to modify their physicochemical properties.

Basic Information

Product Name	2-Iodo-5-(Trifluoromethyl)Benzyl Alcohol
CAS No.	702641-05-2
Molecular Formula	C8H6F3IO
Molecular Weight	302.04 g/mol
Synonyms	[2-Iodo-5-(trifluoromethyl)phenyl]methanol; (2-Iodo-5-(trifluoromethyl)phenyl)methanol; 2-Iodo-α-(trifluoromethyl)benzyl alcohol; 1-Iodo-4-(hydroxymethyl)-2-(trifluoromethyl)benzene; 2-Iodo-5-trifluoromethylbenzyl alcohol; Benzyl alcohol, 2-iodo-5-(trifluoromethyl)-; CAS 702641-05-2
EINECS	Contact for details

Quality Control

Our 2-Iodo-5-(Trifluoromethyl)Benzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.