Description

Cholecystokinin 39 CAS NO 79955-77-4 is a synthetic peptide fragment of the gastrointestinal hormone cholecystokinin (CCK), specifically the C-terminal 39-amino acid sequence. This compound is a critical research tool for studying the physiological roles of CCK, including its functions in digestion, satiety signaling, and central nervous system activity. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on metabolic disorders, gastrointestinal pharmacology, and neurobiology.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies investigating CCK receptor binding, activation, and downstream signaling pathways.
• Biochemical Assay Development: Serves as a key component in the development and validation of immunoassays (ELISA, RIA) and bioassays for detecting CCK or related peptides.
• Neuroscience Studies: Applied in research exploring the role of CCK as a neuropeptide in anxiety, pain perception, memory, and dopaminergic system modulation.
• Gastrointestinal Physiology: Employed to study CCK's effects on pancreatic enzyme secretion, gallbladder contraction, gastric emptying, and gut motility.
• Drug Discovery & Screening: Acts as a lead compound or target molecule in high-throughput screening campaigns for developing novel therapeutics for obesity, pancreatitis, or anxiety disorders.
• Academic & Clinical Research: Provides a standardized reagent for in vitro and in vivo experimental models to elucidate the complex biology of cholecystokinin.

Basic Information

Product Name	Cholecystokinin 39
CAS No.	79955-77-4
Molecular Formula	C194H298N54O58S2
Molecular Weight	~4478.9 g/mol
Synonyms	CCK-39; Cholecystokinin (1-39); CCK Fragment 1-39; CCK-39 (human); Cholecystokinin-39 Peptide; Sincalide precursor fragment; Pancreozymin fragment; CCK (1-39); H-CCK-39
EINECS	Contact for details

Quality Control

Our Cholecystokinin 39 is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and mass spectrometry (MS) for identity confirmation. Certificates of Analysis (COA) detailing purity, peptide content, and analytical data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This hygroscopic (moisture-sensitive) peptide should be allowed to equilibrate to room temperature in a dry environment before opening to prevent condensation and hydrolysis. Aliquot into single-use vials to minimize freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	Within ± 10% of theoretical composition
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.