Description

H-Ala-Ala-Ala-NH2 HCl is a high-purity, protected tripeptide derivative, specifically the hydrochloride salt of H-Ala-Ala-Ala-NH2. This compound serves as a critical building block and research standard in advanced peptide synthesis and biochemical studies. It is essential for pharmaceutical R&D, academic research, and biotechnology applications requiring defined peptide sequences for drug discovery, enzyme substrate studies, and structural biology.

Application

• Pharmaceutical Intermediate: Used in the solid-phase and solution-phase synthesis of longer, more complex therapeutic peptides and peptidomimetics.
• Biochemical Research: Serves as a standard or substrate in enzymatic assays to study protease (e.g., elastase) activity, specificity, and inhibition kinetics.
• Academic Studies: Employed in universities and research institutes for investigating peptide structure-activity relationships (SAR), folding, and stability.
• Reference Standard: Utilized as a high-purity calibrant in analytical methods development for peptide quantification using HPLC, LC-MS, or other techniques.
• Cosmetic Peptide Synthesis: Acts as a precursor in the development of bioactive peptide ingredients for advanced skincare formulations.

Basic Information

Product Name	H-Ala-Ala-Ala-NH2 HCl
CAS No.	79955-53-6
Molecular Formula	C9H18N4O3 • HCl
Molecular Weight	278.73 g/mol
Synonyms	Alanyl-Alanyl-Alaninamide Hydrochloride; H-Ala-Ala-Ala-NH2 • HCl; AAA-NH2 HCl; Tri-L-alaninamide Hydrochloride; L-Alanyl-L-alanyl-L-alaninamide Hydrochloride; (S)-2-((S)-2-((S)-2-Amino-3-methylbutanamido)propanamido)propanamide Hydrochloride; A-A-A-NH2 HCl; Alanine Tripeptide Amide HCl
EINECS	Contact for details

Quality Control

Our H-Ala-Ala-Ala-NH2 HCl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric purity, and identity confirmation via mass spectrometry and IR spectroscopy. Certificates of Analysis (COA) with detailed chromatograms are provided to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.