Description

4-(4-Chloroquinazolin-2-Yl)-N,n-Dimethylaniline is a specialized quinazoline derivative, a high-value chemical intermediate prized for its role in advanced organic synthesis. This compound is critical for research and development in the pharmaceutical and agrochemical sectors, where it serves as a key building block for creating novel active molecules. It is primarily sought after by R&D chemists, process development scientists, and manufacturers engaged in the synthesis of complex heterocyclic compounds for potential therapeutic and crop protection applications.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of targeted kinase inhibitors and other biologically active quinazoline-based compounds for oncology and other therapeutic areas.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Organic Synthesis & Material Science: Serves as a versatile intermediate for constructing complex heterocyclic frameworks used in advanced materials and functional dyes.
• Academic & Contract Research: Essential for medicinal chemistry programs and discovery research in academic institutions and CROs (Contract Research Organizations).
• Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial production.

Basic Information

Product Name	4-(4-Chloroquinazolin-2-Yl)-N,n-Dimethylaniline
CAS No.	79916-53-3
Molecular Formula	C16H14ClN3
Molecular Weight	283.76 g/mol
Synonyms	N,N-Dimethyl-4-(4-chloroquinazolin-2-yl)aniline; 2-[4-(Dimethylamino)phenyl]-4-chloroquinazoline; 4-Chloro-2-[4-(dimethylamino)phenyl]quinazoline; 4-(4-Chloro-2-quinazolinyl)-N,N-dimethylaniline; 79916-53-3; 4-(4-Chloroquinazolin-2-yl)-N,N-dimethylbenzenamine
EINECS	Contact for details

Quality Control

Our 4-(4-Chloroquinazolin-2-Yl)-N,n-Dimethylaniline is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality system supports development under cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.