Description

(+)-2-[2-(3,5-Dichloro-2-Methoxyphenoxy)Ethyl]-1-Ethylpyrrolidinium Hydrochloride is a high-purity, chiral pyrrolidinium salt of significant interest in advanced pharmaceutical synthesis and chemical research. Its value lies in its role as a sophisticated intermediate or building block for the development of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological or receptor-specific pathways. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable access to structurally complex, enantiomerically pure materials.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the research and scale-up of new therapeutic agents.
• Chemical Biology Research: Used as a tool compound or ligand in studying enzyme inhibition and receptor binding assays.
• Agrochemical Synthesis: Potential intermediate for developing advanced, enantiomerically pure crop protection agents.
• Asymmetric Catalysis: May be utilized in the development of chiral catalysts or ionic liquids for stereoselective transformations.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in regulatory submissions.

Basic Information

Product Name	(+)-2-[2-(3,5-Dichloro-2-Methoxyphenoxy)Ethyl]-1-Ethylpyrrolidinium Hydrochloride
CAS No.	79893-50-8
Molecular Formula	C16H24Cl3NO2
Molecular Weight	376.73 g/mol
Synonyms	(+)-1-Ethyl-2-[2-(3,5-dichloro-2-methoxyphenoxy)ethyl]pyrrolidinium chloride; (R)-2-[2-(3,5-Dichloro-2-methoxyphenoxy)ethyl]-1-ethylpyrrolidinium chloride; L-771,688; L771688; (R)-L-771,688 hydrochloride; Pyrrolidinium, 2-[2-(3,5-dichloro-2-methoxyphenoxy)ethyl]-1-ethyl-, chloride, (2R)-; (2R)-2-[2-(3,5-Dichloro-2-methoxyphenoxy)ethyl]-1-ethylpyrrolidin-1-ium chloride
EINECS	Contact for details

Quality Control

Our (+)-2-[2-(3,5-Dichloro-2-Methoxyphenoxy)Ethyl]-1-Ethylpyrrolidinium Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure identity, potency, and purity meet exacting standards. Certificates of Analysis (COA) detailing all relevant specifications are provided and can be tailored to support regulatory filings (e.g., FDA, EMA).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Enantiomeric Excess)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.