Description

L-Tryptophan, 5-Hydroxy-, Methyl Ester is a chemically modified derivative of the essential amino acid tryptophan, specifically esterified at the carboxyl group. This compound is a crucial synthetic intermediate and research chemical, valued for its role in the synthesis of more complex bioactive molecules, including pharmaceuticals and biochemical probes. It is primarily utilized by research institutions, pharmaceutical development labs, and fine chemical manufacturers engaged in neurochemistry, drug discovery, and advanced organic synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of serotonergic agents, melatonin analogs, and other neurologically active compounds.
• Biochemical Research: Used as a precursor in metabolic pathway studies and for probing enzyme mechanisms related to tryptophan metabolism.
• Organic Synthesis: Serves as a chiral starting material or protected intermediate for constructing complex natural products and peptidomimetics.
• Reference Standard: Employed as an analytical standard in HPLC or LC-MS methods for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	L-Tryptophan, 5-Hydroxy-, Methyl Ester
CAS No.	79812-02-5
Molecular Formula	C13H16N2O3
Molecular Weight	248.28 g/mol
Synonyms	5-Hydroxy-L-tryptophan methyl ester; Methyl 5-hydroxy-L-tryptophanate; 5-HTP methyl ester; (S)-2-Amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid methyl ester; 5-Hydroxytryptophan methyl ester; L-5-HTP methyl ester; 5-Hydroxy-L-tryptophan, methyl ester; 5-Hydroxytryptophan, methyl ester, L-
EINECS	Contact for details

Quality Control

Our L-Tryptophan, 5-Hydroxy-, Methyl Ester is produced under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including identity confirmation by IR and NMR, purity assessment by HPLC, and chiral purity verification. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.