Description

n-Acetylmuramyl-Alanylglutamine Methyl Ester is a synthetic derivative of muramyl dipeptide (MDP), a key immunostimulatory component of bacterial peptidoglycan. This compound is of significant interest for its role in modulating immune responses and serves as a crucial intermediate in advanced pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the fields of immunology, vaccine adjuvants, and novel therapeutic agent synthesis.

Application

• Immunological Research: As a defined synthetic analog of MDP for studying innate immune receptor activation (e.g., NOD2) and signaling pathways.
• Vaccine Adjuvant Development: Investigation and formulation of next-generation adjuvants to enhance vaccine efficacy and specificity.
• Pharmaceutical Intermediate: Serving as a key building block in the synthesis of more complex immunomodulatory compounds and prodrugs.
• Biochemical Tool Compound: Used in in vitro and in vivo assays to probe host-pathogen interactions and inflammatory responses.
• Reference Standard: Providing a high-purity standard for analytical method development and quality control in related API manufacturing.

Basic Information

Product Name	n-Acetylmuramyl-Alanylglutamine Methyl Ester
CAS No.	79787-27-2
Molecular Formula	C22H38N4O12
Molecular Weight	550.56 g/mol
Synonyms	Ac-MDP Methyl Ester; N-Acetylmuramyl-L-alanyl-D-isoglutamine Methyl Ester; MDP Methyl Ester; L-Ala-D-isoGln Methyl Ester Muramyl Derivative; MurNAc-L-Ala-D-iGln-OMe; N-Acetylmuramyl-Ala-Gln Methyl Ester; Immunoadjuvant Peptide Derivative; 79787-27-2
EINECS	Contact for details

Quality Control

Our n-Acetylmuramyl-Alanylglutamine Methyl Ester is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.