Description

2,4-Difluorophenylglyoxal Hydrate is a high-purity, versatile fluorinated building block essential for advanced organic synthesis. Its value lies in the reactive glyoxal and difluorophenyl groups, which enable precise molecular construction in complex chemical environments. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a crucial starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Fluorinated Heterocycle Construction: Enables the efficient preparation of fluorinated quinoxalines, imidazoles, and other nitrogen-containing heterocycles of high commercial interest.
• Material Science Research: Employed in the creation of novel fluorinated organic materials, including monomers for specialty polymers and liquid crystals.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	2,4-Difluorophenylglyoxal Hydrate
CAS No.	79784-36-4
Molecular Formula	C8H6F2O3 • xH2O
Molecular Weight	188.13 (Anhydrous basis)
Synonyms	2,4-Difluorobenzoylformaldehyde Hydrate; (2,4-Difluorophenyl)(oxo)acetaldehyde Hydrate; 2,4-Difluorophenylglyoxal Monohydrate; α-Oxo-2,4-difluorobenzeneacetaldehyde Hydrate; Glyoxal, (2,4-difluorophenyl)-, Hydrate; 2,4-DFPG Hydrate
EINECS	Contact for details

Quality Control

Our 2,4-Difluorophenylglyoxal Hydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. This compound is easily oxidized; ensure containers are sealed immediately after use to minimize exposure to air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 3.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.