Description

S(+)-Propylnorapomorphine Hcl is a high-purity, enantiomerically pure derivative of apomorphine, a key compound in neuropharmacological research. Its primary value lies in its potent and selective dopaminergic activity, making it an essential reference standard and research chemical for studying central nervous system functions and disorders. This compound is critically needed by pharmaceutical R&D laboratories, academic research institutions, and analytical facilities focused on neuroscience, Parkinson's disease research, and receptor pharmacology.

Application

• Pharmacological Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical analysis.
• Neuroscience Research: A critical tool for in vitro and in vivo studies targeting dopamine D1 and D2 receptor subtypes to understand signaling pathways and neural mechanisms.
• Drug Discovery & Development: Serves as a lead compound or a biochemical probe for the design and screening of novel therapeutics for Parkinson's disease and other dopaminergic disorders.
• Metabolic and Pharmacokinetic Studies: Employed in ADME (Absorption, Distribution, Metabolism, Excretion) research to investigate the behavior of apomorphine analogs.
• Academic & Institutional Research: Utilized in university and hospital labs for fundamental research into the biochemistry of the basal ganglia and motor control.

Basic Information

Product Name	S(+)-Propylnorapomorphine Hcl
CAS No.	79703-31-4
Molecular Formula	C18H20ClNO2
Molecular Weight	317.81 g/mol
Synonyms	(6aR)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol Hydrochloride; (+)-Propylnorapomorphine Hydrochloride; S-Propylnorapomorphine HCl; (S)-Propylnorapomorphine Hydrochloride; PNA HCl; 10,11-Dihydroxy-6-propylaporphine Hydrochloride; (6aR)-10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline Hydrochloride
EINECS	Contact for details

Quality Control

Our S(+)-Propylnorapomorphine Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC, identity confirmation by IR and MS, and stringent control of related substances. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with our rigorous in-house specifications for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (S-enantiomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.