Description

α-Methyl-5-Pyrimidinemethanol is a versatile pyrimidine derivative, a key heterocyclic building block in advanced organic synthesis. This compound matters for its role as a crucial intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where precise molecular architecture is paramount. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to construct complex molecules with high purity and reliability.

Application

• Pharmaceutical Intermediate: A critical synthon for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where the pyrimidine core imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or light-emitting components.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic and Industrial R&D: Fundamental building block in medicinal chemistry and process chemistry research programs for exploring new chemical entities.

Basic Information

Product Name	α-Methyl-5-Pyrimidinemethanol
CAS No.	79691-74-0
Molecular Formula	C6H8N2O
Molecular Weight	124.14 g/mol
Synonyms	5-(Hydroxymethyl)-2-methylpyrimidine; 2-Methyl-5-pyrimidinemethanol; (5-Pyrimidinyl)methanol, 2-methyl-; α-Methyl-5-pyrimidinemethanol; 2-Methylpyrimidine-5-methanol
EINECS	Contact for details

Quality Control

Our α-Methyl-5-Pyrimidinemethanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.