Description

4-Chloro-1-Methylquinazolin-2(1H)-One is a versatile and high-purity heterocyclic building block, primarily utilized as a key synthetic intermediate in advanced organic chemistry. Its core value lies in enabling the efficient construction of complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). This compound is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of quinazoline-based drug candidates, including potential kinase inhibitors and other therapeutic agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactive quinazolinone scaffold.
• Chemical Synthesis Building Block: Serves as a versatile starting material for further functionalization, enabling the creation of diverse chemical libraries for screening.
• Material Science Research: Investigated for the synthesis of organic electronic materials and advanced polymers due to its fused aromatic structure.
• Academic & R&D Laboratories: Employed in methodological studies and as a reference standard in analytical chemistry and process development.

Basic Information

Product Name	4-Chloro-1-Methylquinazolin-2(1H)-One
CAS No.	79689-39-7
Molecular Formula	C9H7ClN2O
Molecular Weight	194.62 g/mol
Synonyms	4-Chloro-1-methyl-2(1H)-quinazolinone; 4-Chloro-1-methylquinazolin-2-one; 1-Methyl-4-chloroquinazolin-2(1H)-one; 4-Chloro-1-methyl-1,2-dihydroquinazolin-2-one; 4-Chloro-1-methyl-2-quinazolinone; 79689-39-7; 4-Chloro-1-methylquinazolin-2-ol (tautomer)
EINECS	Contact for details

Quality Control

Our 4-Chloro-1-Methylquinazolin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor quality protocols to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.