Description

2-(Benzylthio)-5-Bromopyrimidine is a specialized brominated pyrimidine derivative functionalized with a benzylthio group, serving as a high-value synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for applications such as nucleoside analog synthesis and the creation of novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for antiviral and anticancer nucleoside analogs.
• Agrochemical Research: Used in the development of new herbicides and fungicides that target specific biological pathways.
• Material Science: Serves as a precursor for organic electronic materials and liquid crystals due to its conjugated pyrimidine core.
• Chemical Biology: Employed in the synthesis of probes and inhibitors for studying enzyme mechanisms and protein interactions.
• Cross-Coupling Reactions: The bromine atom makes it a suitable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create diverse biaryl structures.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and custom synthesis houses to fulfill client-specific molecular targets.

Basic Information

Product Name	2-(Benzylthio)-5-Bromopyrimidine
CAS No.	79686-18-3
Molecular Formula	C11H9BrN2S
Molecular Weight	281.17 g/mol
Synonyms	5-Bromo-2-(benzylthio)pyrimidine; 2-(Benzylsulfanyl)-5-bromopyrimidine; 5-Bromo-2-(phenylmethylthio)pyrimidine; 2-Benzylthio-5-bromopyrimidine; Pyrimidine, 5-bromo-2-[(phenylmethyl)thio]-; 79686-18-3; 5-Bromo-2-benzylthiopyrimidine
EINECS	Contact for details

Quality Control

Our 2-(Benzylthio)-5-Bromopyrimidine is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with data from techniques including HPLC, NMR, and mass spectrometry. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.