Description

2-(2-Thenyl)Sulfonyl-5-Bromopyrimidine is a specialized brominated pyrimidine derivative functionalized with a thenylsulfonyl group, serving as a high-value synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for targeted synthesis and medicinal chemistry applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting kinase inhibition or other biological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or pesticides that require a brominated heterocyclic core.
• Material Science: Potential precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Chemical Biology: Useful as a probe or linker in bioconjugation chemistry due to the reactive bromine and sulfonyl groups.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic & Industrial R&D: Employed in exploratory research for method development and discovering new chemical reactions.

Basic Information

Product Name	2-(2-Thenyl)Sulfonyl-5-Bromopyrimidine
CAS No.	79685-33-9
Molecular Formula	C9H7BrN2O2S2
Molecular Weight	335.20 g/mol
Synonyms	5-Bromo-2-[(thiophen-2-ylmethyl)sulfonyl]pyrimidine; 2-[(2-Thienylmethyl)sulfonyl]-5-bromopyrimidine; 5-Bromo-2-((2-thienylmethyl)sulfonyl)pyrimidine; 2-(2-Thienylmethylsulfonyl)-5-bromopyrimidine; 5-Bromo-2-(2-thienylmethylsulfonyl)pyrimidine; 2-(2-Thenylsulfonyl)-5-bromopyrimidine; 79685-33-9; 2-(2-Thienylmethylsulfonyl)-5-bromopyrimidine
EINECS	Contact for details

Quality Control

Our 2-(2-Thenyl)Sulfonyl-5-Bromopyrimidine is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications such as assay (HPLC), related substances, and physical characteristics. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric humidity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.