Description

3,5-Difluorobenzyl Alcohol is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms on the benzyl alcohol core, which can dramatically influence the electronic properties, metabolic stability, and binding affinity of target molecules. This compound is primarily needed by research and development laboratories and production facilities in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of modern pesticides and herbicides, where the difluorobenzyl moiety can enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays, leveraging fluorine's impact on polarity and stability.
• Organic Light-Emitting Diodes (OLEDs): Employed as a building block for electron-transport or host materials in OLED devices.
• Polymer Modification: Acts as a monomer or cross-linking agent to introduce fluorine into polymer backbones, improving chemical resistance and surface properties.
• Chemical Research & Development: A valuable reagent for exploring new fluorination chemistry, Suzuki-Miyaura cross-coupling reactions, and as a protecting group precursor.

Basic Information

Product Name	3,5-Difluorobenzyl Alcohol
CAS No.	79538-20-8
Molecular Formula	C7H6F2O
Molecular Weight	144.12 g/mol
Synonyms	(3,5-Difluorophenyl)methanol; 3,5-Difluorobenzenemethanol; α,3,5-Trifluoro-p-tolyl alcohol; 3,5-Difluorobenzylalcohol; 1-(Hydroxymethyl)-3,5-difluorobenzene; 3,5-DFBA; 79538-20-8
EINECS	Contact for details

Quality Control

Our 3,5-Difluorobenzyl Alcohol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure it meets the high-purity standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥98.0%
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.