Description

Z-His-Trp-Oh CAS NO 79479-33-7 is a high-purity, protected dipeptide derivative consisting of histidine and tryptophan amino acids. This compound serves as a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled construction of complex peptides and proteins. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors who require reliable, high-quality intermediates for drug discovery, peptide therapeutics, and biochemical research.

Application

• Pharmaceutical Intermediate: A key raw material for the synthesis of peptide-based active pharmaceutical ingredients (APIs) and therapeutic peptides.
• Biochemical Research: Used as a protected amino acid sequence in academic and industrial research for studying protein structure, function, and interactions.
• Peptide Library Synthesis: Employed in combinatorial chemistry to create diverse peptide libraries for high-throughput screening in drug discovery.
• Cosmetic Peptide Synthesis: A precursor for bioactive peptides used in advanced skincare and cosmetic formulations.
• Enzyme Substrate Analogues: Useful in the development of specific enzyme inhibitors or substrates for diagnostic and research applications.

Basic Information

Product Name	Z-His-Trp-Oh
CAS No.	79479-33-7
Molecular Formula	C25H26N6O5
Molecular Weight	490.51 g/mol
Synonyms	Z-His-Trp-OH; N-α-Carbobenzoxy-L-histidyl-L-tryptophan; CBZ-L-Histidyl-L-Tryptophan; Z-L-His-L-Trp-OH; Benzyloxycarbonyl-L-histidyl-L-tryptophan; N-CBZ-L-histidyl-L-tryptophan; (S)-2-(((S)-1-((((Benzyloxy)carbonyl)amino)-3-(1H-imidazol-4-yl)propan-2-yl)carbamoyl)-1H-indol-3-yl)acetic acid; L-Histidine, N2-[(phenylmethoxy)carbonyl]-L-tryptophan
EINECS	Contact for details

Quality Control

Our Z-His-Trp-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.