Description

Z-Ala-His-Oh is a protected dipeptide derivative, specifically the Z-protected form of the alanyl-histidine dipeptide. This compound is a crucial building block in solid-phase peptide synthesis (SPPS), enabling the controlled construction of complex peptides and proteins for research and development. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for drug discovery, proteomics, and the synthesis of bioactive peptides.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental protected amino acid derivative for the sequential assembly of custom peptides.
• Pharmaceutical Research & Development: Used as an intermediate in the synthesis of potential therapeutic peptides targeting various diseases.
• Bioconjugation & Probe Development: Serves as a precursor for creating labeled peptides used in diagnostic assays and imaging studies.
• Enzyme Substrate & Inhibitor Synthesis: Employed to create specific peptide sequences for studying enzyme mechanisms and kinetics.
• Biomaterials & Tissue Engineering: Incorporated into designer peptide scaffolds and hydrogels that mimic natural extracellular matrices.
• Chemical Biology Studies: Used to investigate protein-protein interactions and signal transduction pathways using synthetic peptide tools.

Basic Information

Product Name	Z-Ala-His-Oh
CAS No.	79458-92-7
Molecular Formula	C₁₇H₂₂N₄O₆
Molecular Weight	378.38 g/mol
Synonyms	N-[(Benzyloxy)carbonyl]-L-alanyl-L-histidine; Z-L-Ala-L-His-OH; CBZ-L-Alanyl-L-histidine; N-Carbobenzoxy-L-alanyl-L-histidine; Nα-Cbz-L-alanyl-L-histidine; (S)-2-((((Benzyloxy)carbonyl)amino)propanoyl)amino)-3-(1H-imidazol-4-yl)propanoic acid; L-Alanine, N-[(phenylmethoxy)carbonyl]-, (S)-2-[[(S)-2-amino-1-hydroxy-3-(1H-imidazol-4-yl)propylidene]amino]-; Z-Ala-His
EINECS	Contact for details

Quality Control

Our Z-Ala-His-Oh is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.