Description

H-Lys(Me)2-Oh·Hcl is a protected derivative of the essential amino acid L-lysine, specifically featuring dimethylation on the ε-amino group. This modification is critical for its primary role as a key building block in solid-phase peptide synthesis (SPPS), where it prevents unwanted side reactions and enables the controlled construction of complex peptide sequences. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors developing therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a fundamental, protected amino acid monomer for the automated synthesis of custom and therapeutic peptides.
• Pharmaceutical Intermediates: Used in the research and development of novel peptide-based drugs targeting metabolic disorders, oncology, and infectious diseases.
• Bioconjugation & Labeling: The protected amine group allows for selective deprotection and subsequent conjugation with fluorescent dyes, biotin, or other functional molecules.
• Biochemical Research: Employed in studying enzyme-substrate interactions, protein engineering, and structure-activity relationships (SAR) of lysine-containing peptides.
• Antibody-Drug Conjugate (ADC) Development: Acts as a specialized linker or spacer component in the design of next-generation targeted cancer therapies.

Basic Information

Product Name	H-Lys(Me)2-Oh·Hcl
CAS No.	79416-87-8
Molecular Formula	C8H19N3O2·HCl
Molecular Weight	225.72 g/mol (Free base: 189.26 g/mol)
Synonyms	Nε,Nε-Dimethyl-L-lysine hydrochloride; (S)-2,6-Diamino-N,N-dimethylhexanamide hydrochloride; Lys(Me)2-OH·HCl; Fmoc-Lys(Me)2-OH precursor; N6,N6-Dimethyllysine HCl; Protected L-lysine derivative; Dimethyllysine hydrochloride
EINECS	Contact for details

Quality Control

Our H-Lys(Me)2-Oh·Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and NMR for structural confirmation, to ensure it meets the stringent requirements of peptide synthesis. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical R&D and cGMP manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.2%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.