Description

Zervamicin-Ic is a specialized peptide antibiotic belonging to the zervamicin family, known for its potent ionophoric activity and selective membrane-disrupting properties. This compound is critical for advanced research in microbiology and structural biology, particularly in studies of ion channel formation and antimicrobial mechanisms. It serves as an essential tool for pharmaceutical R&D, biotechnology, and academic laboratories focused on developing novel therapeutic agents and understanding peptide-lipid interactions.

Application

• Antimicrobial Research: Used as a reference standard and active agent in studies targeting Gram-positive bacteria and fungi.
• Ion Channel Studies: Serves as a model compound for investigating the structure and function of voltage-gated or ligand-gated ion channels in synthetic membranes.
• Pharmaceutical Development: A key intermediate or reference material in the R&D of novel peptide-based antibiotics and antifungal agents.
• Biophysical Analysis: Employed in spectroscopic studies (NMR, CD) to analyze peptide conformation, membrane insertion, and lipid bilayer interactions.
• Biochemical Reagent: Used in enzymatic assays and studies of membrane permeability and cellular transport mechanisms.
• Academic & Institutional Research: A vital tool for universities and research institutes conducting fundamental research in chemical biology and medicinal chemistry.

Basic Information

Product Name	Zervamicin-Ic
CAS No.	79392-51-1
Molecular Formula	C58H94N14O15
Molecular Weight	1203.5 g/mol
Synonyms	Zervamicin Ic; Antibiotic IA 1986; Zervamicin; L-Gln-L-Leu-L-Hyp-L-Aib-L-Iva-L-Hyp-L-Aib-L-Hyp-L-Aib-L-Iva-L-Hyp-L-Gln-L-Hyp-L-Aib-L-Hyp-L-Ileol; IA-1986; Peptide antibiotic IA-1986; Zervamicin I; Zervamicin IC Peptide
EINECS	Contact for details

Quality Control

Our Zervamicin-Ic is produced and handled under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and specific biological activity assays where applicable. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Specific Optical Rotation	Contact for details
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.