Description

5-Iodo-2-Pyrimidone is a halogenated pyrimidine derivative, a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its reactivity, serving as a key precursor for the development of complex molecules, particularly in pharmaceutical and agrochemical research. This compound is essential for researchers and manufacturers in the life sciences sector who require high-purity intermediates for drug discovery, material science, and the synthesis of nucleoside analogs.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), especially for antiviral and anticancer drug candidates.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its heterocyclic structure for biological activity.
• Nucleoside & Nucleotide Chemistry: Serves as a precursor for modified nucleosides used in biochemical research and diagnostic applications.
• Material Science: Employed in the synthesis of organic electronic materials, ligands for metal complexes, and specialty polymers.
• Cross-Coupling Reactions: The iodine atom makes it a valuable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex biaryl structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme mechanisms.

Basic Information

Product Name	5-Iodo-2-Pyrimidone
CAS No.	79387-69-2
Molecular Formula	C4H3IN2O
Molecular Weight	221.98 g/mol
Synonyms	5-Iodopyrimidin-2(1H)-one; 2-Hydroxy-5-iodopyrimidine; 5-Iodo-1H-pyrimidin-2-one; 5-Iodo-2-hydroxypyrimidine; 5-Iodouracil (tautomer); 5-Iodo-2-pyrimidinol; 79387-69-2 (CAS)
EINECS	Contact for details

Quality Control

Our 5-Iodo-2-Pyrimidone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.