Description

H-Pro-Val-Asp-Oh is a high-purity synthetic peptide building block, also known by its CAS number 79366-75-9. This compound serves as a critical intermediate in the synthesis of complex peptides and peptidomimetics, where precise sequence control is paramount. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing novel therapeutic agents and diagnostic tools.

Application

• Pharmaceutical Research & Development: A key intermediate in the solid-phase and solution-phase synthesis of target peptide sequences for drug discovery programs.
• Peptidomimetic Synthesis: Used to construct non-natural peptide analogs with enhanced stability, bioavailability, or biological activity.
• Bioconjugation & Labeling: Serves as a starting material for creating peptide-based probes, tags, and linkers for diagnostic and imaging applications.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and proteomics research to investigate biological pathways.
• Cosmeceutical Development: Potential use as a precursor for bioactive peptide sequences in advanced skincare formulations.

Basic Information

Product Name	H-Pro-Val-Asp-Oh
CAS No.	79366-75-9
Molecular Formula	C15H23N3O6
Molecular Weight	341.36 g/mol
Synonyms	L-Prolyl-L-valyl-L-aspartic acid; Pro-Val-Asp-OH; H-Pro-Val-Asp-OH; L-Aspartic acid, L-prolyl-L-valyl-; Aspartic acid, prolylvalyl-; PVDA; (S)-2-((S)-2-((S)-Pyrrolidine-2-carboxamido)-3-methylbutanamido)succinic acid; Pro-Val-Asp
EINECS	Contact for details

Quality Control

Our H-Pro-Val-Asp-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric integrity, and identity confirmation via mass spectrometry (MS) and infrared spectroscopy (IR). Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.