Description

Esafloxacin is a synthetic fluoroquinolone antibiotic known for its potent broad-spectrum antibacterial activity. Its primary value lies in its efficacy against a wide range of Gram-positive and Gram-negative bacteria, including resistant strains, making it a critical intermediate in advanced pharmaceutical research and development. This compound is essential for researchers and manufacturers in the pharmaceutical industry focused on developing new antibacterial agents and veterinary medicines. Esafloxacin CAS NO 79286-77-4 represents a high-purity chemical building block for creating next-generation therapeutic solutions.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of advanced fluoroquinolone antibiotic APIs (Active Pharmaceutical Ingredients).
• Antibacterial Research: Used in microbiological and pharmacological studies to investigate mechanisms of action and efficacy against resistant bacterial pathogens.
• Veterinary Medicine Development: Employed in R&D for creating antibacterial treatments for livestock and companion animals.
• Reference Standard: Functions as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical laboratories.
• Biochemical Studies: Utilized in research exploring bacterial DNA gyrase and topoisomerase IV inhibition.

Basic Information

Item	Details
Product Name	Esafloxacin
CAS No.	79286-77-4
Molecular Formula	C19H20F2N4O3
Molecular Weight	390.38 g/mol
Synonyms	PD-161148; (RS)-7-(3-Amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid; (±)-Esafloxacin; DL-Esafloxacin; 1,8-Naphthyridine-3-carboxylic acid, 1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-7-(3-amino-1-pyrrolidinyl)-4-oxo-; PD161148
EINECS	Contact for details

Quality Control

Our Esafloxacin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identification by IR and NMR spectroscopy, and stringent control of related substances and residual solvents. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and pharmaceutical intermediate grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.